Investigation of anti-asthmatic potential of dried fruits of Vitis vinifera L. in animal model of bronchial asthma

Table 2 Effect of VVHE on total cells and differential cell count in bronchial fluid (×10⁵ cells/ml) of ovalbumin-sensitized rats

Groups	Total cells	Eosinophils	Lymphocytes	Macrophages	Neutrophils
SAL	7.00 ± 0.52	0.51 ± 0.56	9.92 ± 0.44	5.13 ± 0.52	0.55 ± 0.05
OVA	11.17 ± 0.87^###	8.50 ± 0.44^###	18.37 ± 0.77^###	12.08 ± 0.77^###	5.60 ± 0.46^###
OVA + dex	4.83 ± 0.48***	3.07 ± 0.42***	10.15 ± 0.71***	6.55 ± 0.81***	1.16 ± 0.08***
OVA + VVHE 1	8.11 ± 0.45*	7.11 ± 0.31^ns	14.15 ± 0.75*	10.02 ± 0.63*	3.27 ± 1.53^ns
OVA + VVHE 2	5.83 ± 0.48**	3.85 ± 0.43**	12.32 ± 0.28**	7.76 ± 0.19**	4.01 ± 0.39*

Values shown are mean ± SEM (n = 6)
ns (non-significant) compared to the OVA-sensitized control (OVA)
SAL non-sensitized and vehicle treated control group, OVA OVA-sensitized and vehicle treated control group, OVA + dex OVA-sensitized and dexamethasone, 2.5 mg/kg, b.w, treated group, OVA + VVHE 1 OVA-sensitized and VVHE, 31 mg/kg, treated group, OVA + VVHE 2 OVA-sensitized and VVHE, 42.5 mg/kg, b.w. treated group
^### p < 0.001 compared to non-sensitized control (SAL)
* p < 0.05, ** p < 0.01, and *** p < 0.001

ISSN: 1710-1492