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Table 5 Factors potentially associated with satisfaction with AIT (ESPIA) according to the bivariate and simple regression models

From: Reduced work/academic performance and quality of life in patients with allergic rhinitis and impact of allergen immunotherapy

Factors Satisfaction with AIT (ESPIA)
Adults working Adults studying
n Bivariate analysis Simple Regression n Bivariate analysis Simple regression#
Mean score SD P value* Beta coefficient Mean score SD P value* Beta coefficient
Age (years)           
 <35 180 63.01 25.64 0.040 Excluded 96 65.43 24.3 0.495 Excluded
 ≥35 206 68.08 24.44 6 62.19 17.38
Sex           
 Male 200 66.18 26.49 0.347   45 62.12 25.89 0.35 8.491
 Female 186 65.21 23.58   57 67.71 22.11
Educational level           
 Basic literacy 6 69.79 25.52 0.924   2 42.19 26.52 0.167 Excluded
 Primary level 51 64.65 24.38   5 44.06 37.41
 Secondary level 139 65.19 25.85   56 64.52 22.08
 Completed university           
Duration of AR (years)           
 <9 194 67.88 24.09 0.095   62 67.42 22.68 0.374 Excluded
 ≥9 190 63.67 25.57   39 61.89 25.91
Etiologic allergen           
 Dust mite 111 62.49 25.32 0.118   37 62.4 26.8 0.976 6.757
 Pollen 190 66.68 25.27   41 63.9 21.27
 Both 75 67.51 25   21 75.72 18.44
Familiar history of atopy           
 Yes 214 64.81 26.59 0.689   68 66.11 23.72 0.766 Excluded
 No 166 67.17 23.06   33 64.77 23.73
Number of visits to allergist           
 <3 196 66.07 24.76 0.888   57 65.44 22.73 0.898 Excluded
 ≥3 187 65.22 25.49   45 64.98 25.54
Type of AR           
 Intermittent 118 74.19 20.92 0.000 −9.232 36 71.01 19.02 0.123 −10.012
 Persistent 268 61.98 25.9 65 62.5 25.75
VALERO severity           
 Mild 66 78.6 20.61 0.000 −4.308 14 75.68 23.63 0.079 Excluded
 Moderate 205 63.84 24.7 64 65.65 22.17
 Severe 115 61.66 25.98 24 58.05 26.91
His tory of allergy           
 No 48 66.71 21.47 0.85   13 56.88 27.74 0.223 Excluded
 Yes 338 65.57 25.6   89 66.46 23.2
Type AIT           
 SCIT 231 66.73 26.36 0.184   54 63.28 26.72 0.845 Excluded
 SLIT 141 65.19 22.79   41 67.03 19.43
  1. “Excluded” are the factors discarded by the regression model as potentially associated with productivity impairment
  2. Mean overall scores of the ESPIA questionnaire are obtained from the sum of its items with transformation to a 0–100-point scale
  3. Significance values are in italics
  4. AIT allergen immunotherapy, AR allergic rhinitis, SD standard deviation
  5. * P-value for the bivariate analysis was calculated using Mann–Whitney or Kruskal–Wallis tests for independent samples, with a confidence interval of 95 %
  6. # In the population of adult students, all variables were included in the simple regression due to lack of significance in the initial bivariate analysis