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Table 3 Characteristics of patients and controls used for gene expression experiment

From: Genetic susceptibility to allergic bronchopulmonary aspergillosis in asthma: a genetic association study

Characteristic

ABPA

Non-atopic asthma

Healthy

n

10

10

10

Age (year) (median, IQR)

59.5 year (55.7–66.1)

46.0 year (37.4–57.3)

38.0 year (31.2–51.1)

% Male

40.0 % (4/10)

20 % (2/10)

40 % (4/10)

Asthma (%)

70 % (7/10)

100 % (10/10)

0 % (0/10)

Lung function tests (n)

5

9

N/A

FEV1 % predicted (median, IQR)

75.0 (71.0–80.0)

85.0 (58.0–105.0)

N/A

FVC % predicted (median, IQR)

103.0 (102.0–106.0)

113.0 (89.0–116.0)

N/A

FEV1/FVC ratio (median, IQR)

60.8 (55.0–63.4)

78.0 (46.0–81.0)

N/A

Markers of ABPA

  

N/A

Bronciectasis (%)

80 % (8/10)

50 % (5/10)

N/A

Total serum IgE (kU/L) (median, IQR) (n)

4100 (2650–7075) (10)

71.9 (63.4–110.0) (10)

N/A

Aspergillus specific IgE (kUA/L) (median, IQR) (n)

34.0 (2.9–60.3) (6)

N/A

N/A

  1. The recruitment criteria specified that the asthma control patients had a negative specific IgE or skin test to aspergillus. Therefore Aspergillus specific IgE level was not measured on every patient but was negative when measured
  2. IQR interquartile range