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Table 3 Management of AS—recommendations given to patients/families of children with EoE at CHEO

From: Adrenal suppression in children treated with swallowed fluticasone and oral viscous budesonide for eosinophilic esophagitis

Stress dosing recommended to all patients until normalization of LDST

 Mild illness or fever

20 mg/m2/day hydrocortisone equivalent, divided BID or TID

 Fever >38.5 or vomiting

30 mg/m2/day hydrocortisone equivalent, divided TID

 Severe illness or injury OR unable to tolerate oral GC during illness

ER for IV GC therapy

 Surgery or procedure with anesthesia

Endocrinology consulted for IV GC dosing

Patients with first morning cortisol <185 nmo/L

 Daily glucocorticoid therapy

10 mg/m2/day q am

 Illness/surgery/injury

Stress dosing as outlined above

  1. BID twice daily, TID three times daily, ER emergency department, IV intravenous, q am daily morning