Fig. 5
From: Clinical validation of controlled exposure to birch pollen in the Environmental Exposure Unit (EEU)
Birch allergic participants were phenotyped into EPR, pEPR and DPR according to their TNSS responses. Participants who experienced an initial rise in their TNSS followed by a decrease of 50 % or more by the 6th or 7th hour, with no second rise in symptoms, were defined as early phase responders (EPR). Participants who reported a second rise in symptoms following the 50 % decline were classified as a dual phase responders (DPR), while those who did not report a 50 % reduction in symptoms but rather a relative maintenance of symptoms were defined as protracted EPR (pEPR)