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Table 3 Statistically significant change in TNSS, TRSS, and PNIF when comparing allergic and non-allergic participants and comparing baseline to each time point for allergic participants

From: Clinical validation of controlled exposure to birch pollen in the Environmental Exposure Unit (EEU)

  Time point (minutes) Statistical significance (p)
TNSS: allergic vs non-allergic participants Baseline NS
30 <0.01
60 <0.0001
90 <0.0001
120 <0.0001
150 <0.0001
180 <0.0001
210 <0.0001
240 <0.0001
270 <0.0001
300 <0.0001
330 <0.001
360 <0.05
390 <0.05
420 NS
450 NS
480 NS
TRSS: allergic vs non-allergic participants Baseline NS
30 NS
60 <0.001
90 <0.0001
120 <0.0001
150 <0.0001
180 <0.0001
210 <0.0001
240 <0.0001
270 <0.0001
300 <0.001
330 <0.01
360 NS
390 NS
420 NS
450 NS
480 NS
  Time point (minutes) vs baseline Statistical significance (p)
TNSS: allergic participants, each time point vs baseline 30 <0.0001
60 <0.0001
90 <0.0001
120 <0.0001
150 <0.0001
180 <0.0001
210 <0.0001
240 <0.0001
270 <0.0001
300 <0.0001
330 <0.0001
360 <0.001
390 <0.01
420 <0.05
450 <0.01
480 <0.01
PNIF: Allergic participants, each time point vs baseline 30 <0.05
60 <0.0001
90 <0.0001
120 <0.001
150 <0.0001
180 <0.0001
210 <0.0001
240 <0.001
270 <0.001
300 <0.01
330 <0.05
360 <0.05
390 <0.05
420 NS
450 NS
480 NS
  1. Allergic participants reported statistically significant increase in TNSS and TRSS and reduction in PNIF compared to non-allergic participants at most time points. Within the allergic group, changes in TNSS and PNIF, following allergen exposure, was significantly different from baseline measurements