Fig. 1
From: Airway autoimmune responses in severe eosinophilic asthma following low-dose Mepolizumab therapy
Disease progression timeline of treatments, development of autoimmune response and clinical severity indices. a FEV1 and blood eosinophils (109/L) is plotted on the left Y axis, while sputum eosinophil % on the right Y axis for the given time points. Dotted line represents the upper-limit of normal blood eosinophil level. b Association of FEV1 and sputum anti-EPX IgG (see Additional file 1: online repository for methods) is plotted on the left Y axis, while daily prednisone dose is plotted on the right Y axis. For both, black arrow indicates intravenous solumedrol (except last indicated on Jan-16 refers to 40 mg prednisone burst, tapered down to maintenance 17.5 mg dose)