Medication | Dose | |
---|---|---|
First-line treatment | Epinephrine (1:1000 concentration) | 0.01 mg/kg IM in the mid-outer thigh in health care settings or 0.15 mg of autoinjector IM in the mid-outer thigh in community settings Epinephrine doses may need to be repeated every 5-15 min |
Adjunctive treatment | Albuterol nebulization | 0.15 mg/kg every 20 min × 3 doses (minimum of 2.5 mg per dose) over 5-15 min |
Albuterol MDI inhalation | 2 puffs, 90 μg per puff, with face mask | |
Oxygen | 8-10 L/min through a face mask | |
Diphenhydramine | 1.25 mg/kg administered orally | |
Cetirizine | 2.5 mg administered orally | |
Normal saline (0.9% isotonic solution) or lactated ringers | 20 ml/kg per dose administered over 5 min intravenously | |
Steroids | Prednisolone 1 mg/kg administered orally or Solu-Medrol 1 mg/kg administered intravenously |