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Table 2 Serum periostin (ng/mL) levels at time points during study

From: Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma

Time points

Periostin

Mean (SD)

Median (IQR)

Min to max

Difference from baseline mean (SD)

Difference (95% CI) from baseline log periostina

Overall P value <0.001

Asthma

0 (0800)

53.5 (13.6)

51.7 (41.5–63.7)

33.9–76.2

   

2 (1000)

52.1 (12.5)

51.3 (40.8–63.0)

32–71.4

−1.4 (2.2)

−0.02 (−0.05 to 0.003)

0.08

4 (1200)

51.3 (13.7)

49.3 (39.3–64.8)

29.9–70.8

−2.2 (3.3)

−0.05 (−0.07 to −0.02)

<0.001

6 (1400)

51.0 (12.7)

51.7 (39.4–61.7)

31.2–69.6

−2.5 (2.5)

−0.05 (−0.07 to −0.02)

<0.001

8 (1600)

50.6 (12.4)

52.3 (38.9–60.4)

32.3–70.0

−2.9 (3.7)

−0.05 (−0.08 to −0.03)

<0.001

10 (1800)

50.9 (13.4)

50.3 (38.9–61.2)

30.3–71.6

−2.6 (2.6)

−0.05 (−0.08 to −0.03)

<0.001

Non-asthma

0 (0800)

50.5 (13.0)

49.4 (42.5–62.7)

28.6–70.5

   

2 (1000)

50.3 (13.4)

48.6 (39.7–61.2)

28.7–72.7

−0.2 (2.7)

−0.006 (−0.04 to 0.02)

0.71

4 (1200)

47.7 (12.2)

46.3 (39.5–59.7)

27.7–67.0

−2.8 (2.5)

−0.06 (−0.09 to −0.03)

<0.001

6 (1400)

46.6 (11.3)

45.0 (39.8–53.8)

28.6–65.5

−3.9 (3.6)

−0.08 (−0.11 to −0.05)

<0.001

8 (1600)

46.5 (11.9)

43.8 (38.6–55.9)

27.9–68.2

−4.0 (2.9)

−0.08 (−0.11 to −0.05)

<0.001

10 (1800)

46.2 (11.5)

46.6 (37.7–55.0)

29.2–66.3

−4.2 (3.2)

−0.08 (−0.11 to −0.06)

<0.001

  1. SD standard deviation, IQR interquartile range, CI confidence interval
  2. aDifference from baseline is estimated from the mixed-effects linear model