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Table 3 FeNO (ppb) levels at time points during study

From: Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma

Time points

FeNO

Mean (SD)

Median (IQR)

Min to max

Difference from baseline mean (SD)

Difference (95% CI) from baseline log FeNOa

Overall P value <0.001

Asthma

0 (0800)

26.1 (13.3)

23.5 (16–36)

7.0–55.0

 

2 (1000)

25.1 (13.3)

24.0 (15–34)

7.0–54.0

−1.0 (5.2)

−0.04 (−0.15 to 0.07)

0.44

4 (1200)

25.8 (16.7)

22.0 (13.5–31.5)

7.0–63.0

−0.3 (8.8)

−0.05 (−0.16 to 0.05)

0.32

6 (1400)

22.8 (12.4)

21.0 (13–31)

5.0–51.0

−3.3 (6.1)

−0.16 (−0.26 to −0.05)

0.005

8 (1600)

21.3 (12.9)

19.0 (13.5–24.5)

7.0–58.0

−4.9 (5.7)

−0.22 (−0.33 to −0.12)

<0.001

10 (1800)

21.7 (12.1)

19.5 (12.5–29)

8.0–54.0

−4.4 (4.5)

−0.18 (−0.29 to −0.07)

0.001

Non-asthma

0 (0800)

22.3 (14.1)

19.5 (15.5–24.5)

6.0–68.0

 

2 (1000)

23.6 (14.9)

19.5 (16.5–27.5)

6.0–73.0

1.4 (2.2)

0.06 (−0.05 to 0.18)

0.30

4 (1200)

21.3 (13.9)

17.0 (13.5–27.0)

7.0–66.0

−1.1 (3.0)

−0.05 (−0.17 to 0.06)

0.38

6 (1400)

22.8 (18.6)

16.0 (15.0–26.0)

7.0–88.0

0.4 (6.6)

−0.02 (−0.14 to 0.09)

0.72

8 (1600)

20.9 (15.4)

17.0 (13.0–23.5)

6.0–72.0

−1.4 (5.9)

−0.10 (−0.22 to 0.01)

0.09

10 (1800)

18.5 (11.2)

16.0 (13.0–21.5)

6.0–56.0

−3.8 (5.5)

−0.17 (−0.28 to −0.05)

0.005

  1. SD standard deviation, IQR interquartile range, CI confidence interval, FeNO fraction of exhaled nitric oxide
  2. aDifference from baseline is estimated from the mixed-effects linear model