Day-time variation of serum periostin in asthmatic adults treated with ICS/LABA and adults without asthma

Table 4 Blood eosinophil (×10⁹/L) levels at time points during study

Time points	Blood eosinophil
Time points	Mean (SD)	Median (IQR)	Min to max	Difference (95% CI) from baseline^a	Overall P value = 0.015
Asthma
0 (0800)	0.31 (0.20)	0.25 (0.20–0.35)	0–0.7	–	–
2 (1000)	0.31 (0.20)	0.20 (0.20–0.40)	0.10–0.7	0.006 (−0.03 to 0.04)	0.71
4 (1200)	0.29 (0.20)	0.20 (0.15–0.40)	0.10–0.7	−0.02 (−0.05 to 0.01)	0.26
6 (1400)	0.29 (0.21)	0.2 (0.1–0.4)	0.1–0.8	−0.02 (−0.05 to 0.01)	0.26
8 (1600)	0.31 (0.19)	0.25 (0.20–0.40)	0.1–0.7	0 (−0.03 to 0.03)	0.99
10 (1800) N = 15	0.34 (0.21)	0.30 (0.20–0.40)	0.1–0.8	0.02 (−0.01 to 0.06)	0.20
Non-asthma
0 (0800)	0.19 (0.11)	0.20 (0.10–0.25)	0.10–0.50	–	–
2 (1000)	0.16 (0.10)	0.10 (0.10–0.20)	0.20–0.50	−0.04 (−0.07 to −0.01)	0.023
4 (1200) N = 15	0.13 (0.10)	0.10 (0.10–0.20)	0–0.4	−0.06 (−0.09 to −0.02)	0.001
6 (1400)	0.14 (0.10)	0.10 (0.10–0.20)	0.0–0.3	−0.06 (−0.09 to −0.02)	<0.001
8 (1600)	0.15 (0.08)	0.10 (0.10–0.20)	0.10–0.30	−0.04 (−0.08 to −0.01)	0.008
10 (1800) N = 15	0.17 (0.09)	0.10 (0.10–0.20)	0.10–0.40	−0.03 (−0.06 to 0.01)	0.13

ISSN: 1710-1492