Epigenetic measure | IFNγ CpG-54 | IFNγ CpG-186 | LINE-1 | |||
---|---|---|---|---|---|---|
Dietary factor | Estimate (95% CI) | q-value | Estimate (95% CI) | q-value | Estimate (95% CI) | q-value |
Kilocalories | ||||||
 T3:T1 | 0.46 (−2.46, 3.38) | 0.90 | −0.11 (−4.35, 4.13) | 1.00 | 3.20 (0.82, 5.58) | 0.16* |
 T2:T1 | −0.40 (−2.87, 2.07) | 0.90 | −4.56 (−7.44, −1.69) | 0.09* | 0.00 (−2.45, 2.46) | 1.00 |
Protein | ||||||
 T3:T1 | 2.60 (−0.90, 6.10) | 0.65 | −0.04 (−3.41, 3.32) | 1.00 | 1.62 (−0.79, 4.03) | 0.69 |
 T2:T1 | 2.17 (−0.46, 4.80) | 0.55 | 2.02 (−1.24, 5.27) | 0.71 | 2.67 (0.62, 4.71) | 0.16* |
M-fats | ||||||
 T3:T1 | −1.10 (−3.70, 1.51) | 0.77 | 4.77 (−0.04, 9.57) | 0.36 | 1.14 (−1.23, 3.51) | 0.76 |
 T2:T1 | −2.42 (−4.74, −0.11) | 0.33 | 6.86 (3.11, 10.62) | 0.02* | 1.12 (−1.00, 3.24) | 0.72 |
S-fats | ||||||
T3:T1 | −0.75 (−3.11, 1.61) | 0.83 | 5.11 (−1.08, 11.31) | 0.55 | 1.52 (−1.09, 4.13) | 0.71 |
T2:T1 | 1.02 (−1.91, 3.96) | 0.82 | 3.00 (−2.48, 8.48) | 0.71 | 1.26 (−1.45, 3.97) | 0.76 |
Omega 3:6 ratio | ||||||
 T3:T1 | 1.44 (−1.23, 4.10) | 0.71 | 2.29 (−1.85, 6.44) | 0.71 | −0.09 (−2.70, 2.52) | 0.99 |
 T2:T1 | 3.72 (0.44, 7.01) | 0.29 | 0.24 (−4.72, 5.20) | 0.98 | 0.96 (−1.03, 2.95) | 0.74 |
Selenium | ||||||
 T3:T1 | 0.34 (−2.45, 3.13) | 0.92 | −1.40 (−5.17, 2.38) | 0.81 | 2.32 (−0.15, 4.79) | 0.45 |
 T2:T1 | 1.40 (−0.60, 3.40) | 0.68 | −2.38 (−5.01, 0.24) | 0.45 | −0.18 (−2.69, 2.33) | 0.98 |
Fiber | ||||||
 T3:T1 | 0.53 (−2.31, 3.37) | 0.90 | −4.67 (−9.09, −0.24) | 0.33 | 1.89 (−1.02, 4.80) | 0.69 |
 T2:T1 | 0.19 (−2.29, 2.68) | 0.98 | −2.52 (−6.54, 1.49) | 0.71 | −0.27 (−2.70, 2.16) | 0.94 |
Folate | ||||||
 T3:T1 | 2.93 (0.06, 5.80) | 0.36 | 2.46 (−2.25, 7.17) | 0.72 | 4.29 (2.25, 6.34) | 0.01* |
 T2:T1 | 1.95 (−0.03, 3.93) | 0.36 | −4.05 (−6.18, −1.91) | 0.02* | 0.46 (−1.24, 2.16) | 0.85 |
Methionine | ||||||
 T3:T1 | 0.63 (−2.42, 3.68) | 0.89 | −2.70 (−6.86, 1.45) | 0.69 | 1.12 (−1.78, 4.03) | 0.80 |
 T2:T1 | 0.43 (−2.25, 3.11) | 0.90 | −1.38 (−5.68, 2.92) | 0.83 | 1.58 (−1.04, 4.21) | 0.71 |
Free choline | ||||||
 T3:T1 | 1.33 (−1.08, 3.74) | 0.71 | −2.61 (−5.84, 0.63) | 0.55 | 2.18 (0.54, 3.82) | 0.16* |
 T2:T1 | 1.29 (−1.03, 3.60) | 0.71 | −3.28 (−6.33, −0.24) | 0.29 | 0.01 (−1.82, 1.85) | 1.00 |
Glycpp-choline | ||||||
 T3:T1 | 0.44 (−2.23, 3.12) | 0.90 | −2.81 (−5.95, 0.33) | 0.48 | 0.66 (−1.48, 2.80) | 0.83 |
 T2:T1 | 1.68 (−0.54, 3.89) | 0.65 | −0.31 (−3.84, 3.22) | 0.97 | 0.24 (−1.74, 2.21) | 0.92 |
Pp-choline | ||||||
 T3:T1 | 0.50 (−2.65, 3.65) | 0.90 | −1.77 (−5.27, 1.73) | 0.73 | 0.41 (−1.43, 2.25) | 0.88 |
 T2:T1 | 1.47 (−0.52, 3.46) | 0.65 | −1.54 (−5.83, 2.75) | 0.82 | −2.08 (−4.41, 0.24) | 0.48 |
Ppt-choline | ||||||
 T3:T1 | 1.49 (−1.08, 4.06) | 0.71 | −2.33 (−6.06, 1.39) | 0.71 | 0.64 (−1.66, 2.94) | 0.84 |
 T2:T1 | −0.78 (−3.40, 1.84) | 0.83 | −1.55 (−6.86, 3.76) | 0.83 | −1.66 (−4.03, 0.71) | 0.68 |
Total choline | ||||||
 T3:T1 | 1.29 (−1.06, 3.64) | 0.71 | −3.47 (−6.68, −0.26) | 0.29 | 2.60 (0.60, 4.60) | 0.16* |
 T2:T1 | 0.85 (−1.41, 3.11) | 0.80 | −3.58 (−6.59, −0.58) | 0.28 | 0.42 (−1.88, 2.73) | 0.90 |
Betaine | ||||||
 T3:T1 | −0.00 (−2.50, 2.49) | 1.00 | −4.34 (−7.25, −1.42) | 0.12* | 1.18 (−1.25, 3.62) | 0.74 |
 T2:T1 | 1.52 (−1.21, 4.26) | 0.71 | 1.28 (−4.28, 1.73) | 0.77 | 1.65 (−0.61, 3.91) | 0.65 |
Vitamin B-2 | ||||||
 T3:T1 | 0.62 (−2.44, 3.68) | 0.89 | −4.19 (−7.91, −0.48) | 0.29 | 2.47 (−0.37, 5.32) | 0.51 |
 T2:T1 | 1.41 (−0.74, 3.56) | 0.69 | −4.03 (−7.86, −0.20) | 0.33 | 0.23 (−2.48, 2.94) | 0.97 |
Vitamin B-6 | ||||||
 T3:T1 | 2.05 (−1.04, 5.14) | 0.69 | −6.63 (−11.13, −2.14) | 0.12* | 1.44 (−1.65, 4.52) | 0.76 |
 T2:T1 | 0.66 (−1.80, 3.12) | 0.85 | −6.57 (−10.65, −2.48) | 0.09* | 0.13 (−2.39, 2.65) | 0.98 |
Vitamin B-12 | ||||||
 T3:T1 | 1.12 (−2.31, 4.55) | 0.83 | −2.31 (−7.00, 2.39) | 0.74 | 0.59 (−2.43, 3.60) | 0.90 |
 T2:T1 | 2.21 (−0.48, 4.91) | 0.55 | 1.84 (−2.37, 6.05) | 0.77 | 0.87 (−2.09, 3.82) | 0.83 |