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Table 3 Demographic and clinical data for Chinese patients with new-onset and re-visiting SLE

From: Elevated expression of TIGIT on CD3+CD4+ T cells correlates with disease activity in systemic lupus erythematosus

Categories

New-onset SLE

Re-visiting SLE

N

16

34

Females, n (%)

15 (93.8)

31 (91.4)

Age, mean (SD), years

28.1 (11.1)

38.2 (14.6)

ANA (+, ≥1:100), n (%)

16 (100)

33 (97.1)

Anti-dsDNA, mean (SD), IU/mL

346.6 (329.3)*

165.3 (267.7)

IgG, mean (SD), g/L

19.1 (5.9)

17.0 (9.6)

C3, mean (SD), g/L

0.52 (0.33)

0.63 (0.23)

C4, mean (SD), g/L

0.09 (0.060)*

0.16 (0.050)

ESR, mean (SD), mm/h

62.1 (41.2)*

35.1 (38.0)

SLEDAI score, mean (SD)

8.4 (5.0)

5.5 (4.8)

Lymphocytes, mean (SD), %a

17.1 (1.0)

16.8 (7.9)

CD3+ lymphocytes, mean (SD), %b

68.3 (11.0)

70.3 (9.9)

CD4+ T subset, mean (SD), %c

40.8 (5.4)

47.8 (14.9)

CD4+ T subset, mean (SD), /mL

269.5 (8.7)

330.1 (239.4)

CD8+ T subset, mean (SD), %c

59.2 (5.4)

52.2 (14.9)

CD8+ T subset, mean (SD), /mL

435.8 (97.5)

455.1 (77.1)

Ratio of CD4+/CD8+T, mean (SD)

1.02 (0.85)

1.03 (0.64)

  1. ANA anti-nuclear antibodies, Anti-dsDNA anti double-stranded DNA, C3 complement 3, C4 complement 4, ESR erythrocyte sedimentation rate, IgG immunoglobulin G, SLE systemic lupus erythematosus, SLEDAI SLE disease activity index
  2. * P < 0.05 compared to re-visiting SLE group
  3. aPercentage of total white blood cells in peripheral blood
  4. bPercentage of total lymphocytes in peripheral blood
  5. cPercentage of CD3+ lymphocytes in peripheral blood