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Table 2 Differences between children with mild or moderate-to-severe allergic rhinitis

From: Nasal nitric oxide in allergic rhinitis in children and its relationship to severity and treatment

 

Mild (n = 50)

Moderate+ (n = 44)

P

Age at diagnosis, years

4.5 ± 2.1

4.2 ± 2.1

<0.001

Disease duration, months

12 (4, 24)

24 (8, 48)

<0.001

Post-treatment change in nNO concentration, ppb

−69.5 (−118.0, −36.0)

−191.0 (−301.0, −90.0)

<0.001

RQLO, pointsa

0.17 (0, 0.96)

2.08 (1.02, 2.64)

<0.001

 Inconvenience due to stuffy nose

0 (0, 2)

4 (0, 4.5)

<0.001

 Inconvenience due to sneezing

0 (0, 1)

2 (1, 3)

<0.001

 Inconvenience due to runny nose

0 (0, 1)

2 (0.5, 3)

<0.001

 Inconvenience due to itchy nose

0 (0, 2)

2 (0.5, 4.5)

<0.001

 Inconvenience due to itchy eyes

0 (0, 1)

2 (0, 3.5)

<0.001

 Inconvenience due to watery eyes

0 (0, 0)

1 (0, 1.5)

0.001

 Inconvenience due to red eyes

0 (0, 0)

1 (0, 2)

0.001

 Inconvenience due to swollen eyes

0 (0, 0)

0.5 (0, 1)

<0.001

 Inconvenience due to painful eyes

0 (0, 0)

0 (0, 1)

<0.001

 Rubbing nose or eyes repeatedly

0 (0, 2)

3 (1, 5)

<0.001

 Postnasal drip

0 (0, 2)

3 (1, 5)

<0.001

 Having to carry handkerchiefs

0 (0, 0)

2 (0, 4)

<0.001

 Having to take medications

0 (0, 0)

0 (0, 1)

<0.001

 Interference with leisure activities

0 (0, 0)

1 (0, 3)

<0.001

 Inconvenience due to dry throat

0 (0, 0)

1 (0, 2.5)

<0.001

 Inconvenience due to itchy throat

0 (0, 0)

2 (0, 3)

<0.001

 Inconvenience due to headache

0 (0, 0)

0 (0, 1)

0.054

 Inconvenience due to fatigue

0 (0, 1)

1.5 (0, 3)

<0.001

 Interference with mood

0 (0, 0)

2 (0, 3.5)

<0.001

 Interference with attention

0 (0, 1)

2 (0, 4)

<0.001

 Interference with sleep

0 (0, 1)

1 (0, 2.5)

<0.001

 Frequent nocturnal awakening

0 (0, 1)

1 (0, 2)

0.001

 Irritable/anxiety/angry

0 (0, 1)

2 (0, 4)

<0.001

 Embarrassed because of nasal symptoms

0 (0, 0)

1 (0, 1)

<0.001

  1. Age at diagnosis is presented as mean ± standard deviation and tested by independent sample t-test; the others are shown as median (interquartile range) and tested by Mann–Whitney U test
  2. Italic value indicates significant difference among two groups, P < 0.05
  3. nNO nasal nitric oxide, RQLQ Rhinoconjunctivitis Quality of Life Questionnaire
  4. aScoring system of RQLQ questionnaire: 0 no effect, 1 hardly any effect, 2 mild effect, 3 moderate effect, 4 medium effect, 5 major effect, 6 severe effect
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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