Fig. 6
From: Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor
IL-31RA−/− mice administered intraperitoneally with Cry j 2 exhibit enhanced antigen-specific Th2-mediated antibody responses. Littermate IL-31RA−/− and IL-31RA+/− control mice were intraperitoneally administered once a week with Cry j 2 for induction of antigen-specific Th2 responses. 7 days after three intraperitoneal administrations of Cry j 2, serum from IL-31RA−/− (N = 5) and littermate control IL-31RA+/− (N = 5) mice were collected and assayed for Cry j 2-specific IgE (a), IgG1 (b), IgG2a (c), and IgG2b (d) antibody responses. Data are presented as the mean ± SD. Unpaired t test; *P < 0.05. Paired t test; #P < 0.05, ##P < 0.01