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Table 3 Clinical details on VIT-induced anaphylactic reactions in children and adolescents

From: Safety of 100 µg venom immunotherapy rush protocols in children compared to adults

Patient no.

1

2

3

4

5

History

 Age (years)

7

7

7

15

17

 Sex

F

M

M

F

M

 Causative venom

Bee

Vespula

Vespula

Vespula

Bee

 Severity of anaphylaxis at index sting (grade)

II

II

II

III

II

 Relevant comorbidities

None

None

Asthma

None

None

 Concurrent medication

None

None

Yesa

None

None

VIT-induced anaphylaxis

 Severity (grade)

II

I

I

I

I

 Symptoms

  Urticaria/angioedema

+

+

+

+

+

  Respiratory

+

  Gastrointestinal

+

  Cardiovascular

 Injection protocol

3 days

3 days

3 days

3 days

5 days

 Venom dose prior to reaction (µg)

50

40

50

40

8

 Time interval to injection (minutes)

15

60

120

25

60

 Treatment

  Antihistamine

i.v.

Oral

i.v.

i.v.

Oral

  Steroid

i.v.

  Epinephrine

  Inhalative beta2-adrenergic agonist

+

  1. aInhalative budesonide/formoterol