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Table 2 Characteristics of participants initiating SLIT for HDM allergy

From: Poor sleep is highly associated with house dust mite allergic rhinitis in adults and children

Variable

Statistics

Children n = 843

Adults n = 907

p value

Total n = 1750

Sex

N (missing data)

836 (7)

902 (5)

 

1738 (12)

 Male

N (%)

479 (57.3)

346 (38.4)

<0.001 (S)*

825 (47.5)

Age (years)

N

843

907

 

1738

 

Mean ± SD

10.5 ± 3.5

33.2 ± 11.7

 

22.3 ± 14.3

Family history of allergy

N (%)

656 (77.8)

577 (63.6)

<0.001 (S)*

1233 (70.5)

Polysensitization

N (%)

466 (55.3)

565 (62.3)

0.003 (S)*

1031 (58.9)

Contact with pets

N (missing data)

805 (38)

874 (33)

 

1679 (71)

 Regular contact

N (%)

421 (52.3)

420 (48.1)

0.082 (NS)*

841 (50.1)

Weight

N (missing data)

812 (31)

900 (7)

 

1712 (38)

 Obesity

N (%)

92 (11.3)

79 (8.8)

0.079 (NS)*

171 (9.8)

Moderate or high risk of sleep apnea syndrome

N (%)

148 (16.3)

 

Smoking status

N (missing data)

792 (51)

901 (6)

 

1693 (57)

 Current smoker or currently exposed to passive smoking

N (%)

88 (11.1)

119 (13.2)

0.189 (NS)*

207 (12.2)

Sports activity

N (missing data)

834 (9)

905 (2)

 

1739 (11)

 No regular sports activity

N (%)

411 (49.3)

642 (70.9)

<0.001 (S)*

1053 (60.6)

Rhinitis assessment

N (missing data)

762 (81)

814 (93)

 

1576 (174)

 Persistent rhinitis

N (%)

655 (86.0)

732 (89.9)

0.015 (S)*

1387 (88.0)

 RTSS

Mean ± SD

9.0 ± 3.4

9.8 ± 3.6

<0.001 (S)#

9.5 ± 3.5

 TNSS

Mean ± SD

7.3 ± 2.4

7.7 ± 2.4

<0.001 (S)#

7.5 ± 2.4

Asthma assessment

N

843

907

 

1750

 Associated asthma

N (%)

407 (48.3)

329 (36.3)

<0.001 (S)**

736 (42.1)

 Persistent asthma

N (%)

211 (25.0)

158 (17.4)

<0.001 (S)*

369 (21.1)

Previous treatments within the year before SLIT initiation

N

843

907

 

1750

 Oral antihistamines

N (%)

713 (84.6)

822 (90.6)

<0.001 (S)**

1535 (87.7)

 Nasal corticoids

N (%)

452 (53.6)

529 (58.3)

0.048 (S)**

981 (56.1)

 Asthma medicationsa

N (%)

319 (78.4)

257 (78.1)

0.931 (NS)*

576 (78.3)

  1. RTSS rhinitis total symptom score ranging from 0 to 18, TNSS total nasal symptom score ranging from 0 to 12
  2. * Chi2 Pearson test
  3. ** Fisher test (at least one theoretical number ≤5)
  4. # Wilcoxon-Mann–Whitney test (non-Gaussian variable)
  5. aAt least one long-acting β2-agonist and/or short-acting β2-agonist and/or fixed-dose combination and/or inhaled corticosteroids