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Table 2 Characteristics of participants initiating SLIT for HDM allergy

From: Poor sleep is highly associated with house dust mite allergic rhinitis in adults and children

Variable Statistics Children n = 843 Adults n = 907 p value Total n = 1750
Sex N (missing data) 836 (7) 902 (5)   1738 (12)
 Male N (%) 479 (57.3) 346 (38.4) <0.001 (S)* 825 (47.5)
Age (years) N 843 907   1738
  Mean ± SD 10.5 ± 3.5 33.2 ± 11.7   22.3 ± 14.3
Family history of allergy N (%) 656 (77.8) 577 (63.6) <0.001 (S)* 1233 (70.5)
Polysensitization N (%) 466 (55.3) 565 (62.3) 0.003 (S)* 1031 (58.9)
Contact with pets N (missing data) 805 (38) 874 (33)   1679 (71)
 Regular contact N (%) 421 (52.3) 420 (48.1) 0.082 (NS)* 841 (50.1)
Weight N (missing data) 812 (31) 900 (7)   1712 (38)
 Obesity N (%) 92 (11.3) 79 (8.8) 0.079 (NS)* 171 (9.8)
Moderate or high risk of sleep apnea syndrome N (%) 148 (16.3)  
Smoking status N (missing data) 792 (51) 901 (6)   1693 (57)
 Current smoker or currently exposed to passive smoking N (%) 88 (11.1) 119 (13.2) 0.189 (NS)* 207 (12.2)
Sports activity N (missing data) 834 (9) 905 (2)   1739 (11)
 No regular sports activity N (%) 411 (49.3) 642 (70.9) <0.001 (S)* 1053 (60.6)
Rhinitis assessment N (missing data) 762 (81) 814 (93)   1576 (174)
 Persistent rhinitis N (%) 655 (86.0) 732 (89.9) 0.015 (S)* 1387 (88.0)
 RTSS Mean ± SD 9.0 ± 3.4 9.8 ± 3.6 <0.001 (S)# 9.5 ± 3.5
 TNSS Mean ± SD 7.3 ± 2.4 7.7 ± 2.4 <0.001 (S)# 7.5 ± 2.4
Asthma assessment N 843 907   1750
 Associated asthma N (%) 407 (48.3) 329 (36.3) <0.001 (S)** 736 (42.1)
 Persistent asthma N (%) 211 (25.0) 158 (17.4) <0.001 (S)* 369 (21.1)
Previous treatments within the year before SLIT initiation N 843 907   1750
 Oral antihistamines N (%) 713 (84.6) 822 (90.6) <0.001 (S)** 1535 (87.7)
 Nasal corticoids N (%) 452 (53.6) 529 (58.3) 0.048 (S)** 981 (56.1)
 Asthma medicationsa N (%) 319 (78.4) 257 (78.1) 0.931 (NS)* 576 (78.3)
  1. RTSS rhinitis total symptom score ranging from 0 to 18, TNSS total nasal symptom score ranging from 0 to 12
  2. * Chi2 Pearson test
  3. ** Fisher test (at least one theoretical number ≤5)
  4. # Wilcoxon-Mann–Whitney test (non-Gaussian variable)
  5. aAt least one long-acting β2-agonist and/or short-acting β2-agonist and/or fixed-dose combination and/or inhaled corticosteroids