Fig. 2

The increase of CCR7⁺ memory CD4⁺ T cells is unaffected by common therapeutics. a Percentage of CD45RA⁻CD45RO⁺CCR7⁺ cells in CD3⁺CD4⁺ T cells across non-asthmatic subjects (NAS) and asthma patients (AS) with (Eosinophilic AS) or without (NE AS) blood eosinophilia. b Percentage of CD45RA⁻CD45RO⁺CCR7⁺ cells in CD4⁺ T cells in atopic asthma of different severities based on % predicted FEV1 scores (mild: > 80%, moderate: 60–79%, severe: < 60%). Percentage of CD45RA⁻CD45RO⁺CCR7⁺ cells in CD3⁺CD4⁺ T cells in NAS and AS treated with/without corticosteroids (c, left) oral corticosteroid (OCS) (c, right) and leukotriene inhibitor (d). Analysis based on one-way ANOVA with Tukey test. *P < 0.05, **P < 0.01, ***P < 0.001, n.s.: not significant. Error bars indicate SD