Table 3 Laboratory testing results at different time periods of the patient’s presentation
Laboratory testing | Baseline before recombinant human erythropoietin | Day 2 of initial reaction to intravenous darbepoetin alfa | Day 2 of failed 2-day desensitization to epoetin alfa | During modified desensitization (at 112 IU daily dose) | One month after desensitization |
|---|---|---|---|---|---|
Hemoglobin (g/L) | 7.8 | 7.0 | 6.7 | 6.0 | 9.2 |
Hematocrit (%) | 22.3 | 20.7 | 19.5 | 18.6 | 27.0 |
White blood cells (cells/μL) | 9100 | 10,400 | 13,100 | 13,300 | 10,200 |
Neutrophils (cells/μL) | 3600 | 5700 | 6100 | 8900 | 9200 |
Lymphocytes (cells/μL) | 3600 | 1300 | 2800 | 2400 | 600 |
Monocytes (cells/μL) | 400 | 1000 | 1300 | 1000 | 200 |
Eosinophils (cells/μL) | 1400 | 2400 | 3000 | 900 | 200 |
Basophils (cells/μL) | 100 | 0 | 0 | 100 | 0 |
Aspartate aminotransferase (IU/L) | 34.0 | NM | 14.0 | 15.0 | NM |
Alanine aminotransferase (IU/L) | 33.0 | NM | < 15 | 15.0 | NM |
Blood urea nitrogen (mg/dL) | 51.0 | 54.0 | 59.0 | 9.0 | 30.0 |
Creatine (mg/dL) | 3.2 | 8.1 | 12.9 | 11.6 | 7.5 |