Table 2 Anaphylaxis morbidity epidemiology publications
From: Critical view of anaphylaxis epidemiology: open questions and new perspectives
References | Study location | Study design and anaphylaxis definition chosen | Epidemiological variables suited and outcomes | Number of subjects | Study period | Study anaphylaxis morbidity database |
|---|---|---|---|---|---|---|
Beyer et al. [31] | Germany | Self-reported cases from the general population based on survey questionnaire | Incidence of severe anaphylaxis: 4.5 per 100,000 | 333 | 2008–2010 | Local database |
Buka et al. [32] | United Kingdom | Retrospective observational study based on search terms considering the WAO anaphylaxis definition [7] | Incidence of anaphylaxis: 12.0 per 100,000 person-years | 426 patient episodes | 12 months (2012) | National Health Service (NHS) database |
Campbell et al. [33] | United States of America | Historic-prospective observational cohort study with analysis of medical records based on the NIAID/FAAN diagnostic criteria for anaphylaxis [1] | Prevalence of anaphylaxis: 582 Patients needing more than 1 dose of epinephrine: 8% | 582 | 2010–2013 | National SAS-Display Manager System database |
Cetinkaya et al. [34] | Turkey | Search for ICD-10 anaphylaxis and secondary codes as primary cause of hospitalization | Incidence admissions for anaphylaxis: 11.05 per 100,000 person-years | 114 patients | 12 months (2010–2011) | National database: The Health Directorate Network of Istanbul |
Gibbison et al. [35] | United Kingdom | Retrospective analysis of all physician-diagnosed cases in national audit data from critical care units considering NIAID/FAAN anaphylaxis definition [1] as first or secondary cause of admission | Paediatric admissions with anaphylaxis: 6–23/year Adult admissions with anaphylaxis: 183–331/year | 1350 admissions for anaphylaxis | 2005–2009 | National audits of critical care units in the UK: the Intensive Care National Audit and Research Centre’s (ICNARC) Case Mix Programme (CMP), Scottish Intensive Care Society Audit Group (SICSAG) and Paediatric Intensive Care Audit Network (PICANet) |
Grunau et al. [36] | Canada | Retrospective cohort study with dichotomized algorithm for “anaphylaxis” considering the WAO definition for anaphylaxis [7] | Emergency department visits for anaphylaxis: 23.2 per 100,000 person-years | 496 | 2007–2012 | Local electronic medical records database |
Harduar-Morano et al. [37] | United States of America | Population-based epidemiologic study using national database and selected ICD codes | Incidence of anaphylaxis: 7.5 per 100,000 person-years | 2751 | 2005–2006 | Agency for Health Care Administration |
Jeppesen et al. [38] | Denmark | Population-based cohort study using national database and selected ICD codes | Average hospitalization rate for first-time anaphylactic shock was 64.6 per 1,000,000 person-years | 6707 | 1995–2012 | Danish National Patient Registry and the Danish Civil Registration System |
Kimchi et al. [39] | Canada | Software program applied to prospectively record characters of anaphylaxis cases taking the WAO definition of anaphylaxis [7] | % Anaphylaxis among all calls: 0.31 % Anaphylaxis among calls requiring transport: 0.44 | 104 | 12 months (2013–2014) | Cross Canada Anaphylaxis Registry database |
Lee et al. [40] | United States of America | Population-based incidence study selected by ICD codes | Incidence rate of anaphylaxis was 42 per 100,000 person-years | 2386 | 2001–2010 | Rochester Epidemiology Project linked to the list of all Olmsted County residents |
Mullins et al. [41] | Australia | Population-based epidemiologic study using national database and selected ICD codes | Increase in overall anaphylaxis admission rates: 1.5-fold/7 years | 3.6–17.7 cases/105 population | 2005–2006 and 2011–2012 | Australian National Hospital morbidity database |
Tejedor Alonso et al. [42] | Spain | Population-based epidemiologic study using national database and selected ICD codes | Anaphylaxis admissions in the general population: 1.35–2.38 per 100,000 person-years | 11,336 records | 1998–2011 | Spanish information system for hospital data |
Wood et al. [43] | United States of America | Self-reported cases from the general population based on survey questionnaire considering the main anaphylaxis definitions [1, 3, 6, 7] | Prevalence of anaphylaxis in the general population: 1.6% | 344 | 5 months (2011) | Local database |
Worm et al. [44] | European countries (Austria, Bulgaria, France, Germany, Greece, Ireland, Italy, Poland, Spain and Switzerland) | Data collection from specialized European countries by online questionnaire considering the EAACI-WAO revised nomenclature [45] | Number of anaphylaxis cases: 3333 Recurrence: 34.2% | 3333 | 2011–2014 | European anaphylaxis registry |
Turner et al. [45] | United Kingdom | Population-based epidemiologic study using hospital admission data and selected ICD codes | Number of hospital admissions for anaphylaxis: 1.0–7.0 cases per 100,000 population per annum | Data limited to the number of admissions | 1992–2012 | Hospital episodes statistics database |