Fig. 1

Schematic diagram of OVA-induced allergic rhinitis model. BALB/c mice were sensitized with OVA and aluminum hydroxide on days 0, 7, 14, and 21. All groups except the negative control were sensitized with intranasal instillation with OVA on days 22–30. Artemisinin was nasally administered 1 h before each challenge at 1, 10 or 100 mg/kg on days 22–30. Positive control group was treated with PBS