Table 2 Serum periostin levels at time points in joint replacement group, and ratio of geometric means compared with pre-operative reference baseline value
Visit | N | Periostin mean (SD)a | Change from baseline Mean (SD)a | Ratio of geometric means (95% CI) | P |
|---|---|---|---|---|---|
Pre-operative (reference) | 34 | 54.2 (18.0) | – | – | – |
Within 48 h | 31 | 43.5 (12.5) | − 11.5 (9.7) | 0.80 (0.75–0.86) | < 0.001 |
 Week 1 | 33 | 55.5 (17.8) | 1.4 (12.4) | 1.03 (0.97–1.10) | 0.37 |
 Week 2 | 32 | 79.0 (27.0) | 24.0 (17.3) | 1.44 (1.35–1.54) | < 0.001 |
 Week 4 | 32 | 97.3 (29.2) | 43.6 (1.9) | 1.83 (1.72–1.96) | < 0.001 |
 Week 8 | 31 | 101.3 (31.2) | 46.9 (22.6) | 1.89 (1.77–2.02) | < 0.001 |
 Week 12 | 31 | 89.8 (26.6) | 35.3 (16.3) | 1.67 (1.57–1.79) | < 0.001 |
 Week 26 | 31 | 68.3 (20.7) | 13.8 (12.8) | 1.27 (1.19–1.36) | < 0.001 |