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Table 2 Notable case history related to pediatric EAI use

From: Unintentional injection to the bone with a pediatric epinephrine auto-injector

Age at event, years

6 years (2013)

7 years (2014)

9 years (2017)

Height (cm)

117

122

141

Weight (kg)

17.7

25

30

STBD (with compression, mm)

10.7

11.1

12.1

Suspected/known allergen

Milk

Cake with cashew

“Snack Pack” bakery shop dessert (tapioca, carrageenan)

Symptoms/acute care

MS ingested milk and her caregiver administered the EpiPen Jr® because she thought MS complained of throat itchiness

MS had immediate shortness of breath, hives, throat tightness, and lip swelling

Her mother gave her the EpiPen Jr® in the right mid-anterolateral thigh

Epinephrine worked immediately, and she improved within 30 s

MS had transient shakes, tachycardia, fatigue lasting approximately 3 min

MS was taken to and observed in the Emergency Department. MS complained of pain immediately in her right thigh at the injection site, which has persisted over time

X-ray and ultrasound were negative

MS had an immediate throat swelling and shortness of breath

MS was given 2 doses of epinephrine

Her symptoms improved within minutes

Follow up case notes

In August 2017, MS was examined for bony lesions, fracture, or soft tissue disorders that could explain her continued discomfort and pain

The previous allergic emergency in 2014 requiring the use of her EAI was noted

Negative X-ray and ultrasound of right femur and no evidence of muscular injury or hematoma. No discrete solid or cystic lesions

It was noted that she was skeletally immature

Long-term management

Keep prescribed EpiPen Jr® available

Instructions on how to give the EpiPen Jr® without full muscle compression

Continue strict avoidance of milk, raw peanut, cashew, hazelnut, pecan, and pistachio