TY - JOUR AU - Fernando, Shalinda Jude Arjuna AU - Faiz, Noorul Mifra AU - Handunnetti, Shiroma Mangaika AU - De Silva, Aruna Dharshan AU - Dasanayake, Wasala Mudiyanselage Dhanushka Kumari AU - Wickramasinghe, Geethani Devika AU - Karunatilake, Rathnayake Mudiyanselage Chandima Hasanthi AU - de Silva, Nilhan Rajiva PY - 2018 DA - 2018/09/17 TI - Preliminary study on chronic granulomatous disease in Sri Lanka JO - Allergy, Asthma & Clinical Immunology SP - 37 VL - 14 IS - 1 AB - Chronic granulomatous disease (CGD) is a rare primary immunodeficiency of the phagocytic cells, which results in absent or diminished levels of microbicidal reactive oxygen species. The disease occurs due to germline mutations in the genes encoding the five subunits of NADPH oxidase complex. The present study is a pilot study to understand the clinical and genetic aspects of CGD in Sri Lanka. SN - 1710-1492 UR - https://doi.org/10.1186/s13223-018-0264-7 DO - 10.1186/s13223-018-0264-7 ID - Fernando2018 ER -