Table 3 Patients’ ratings of different aspects of the 500 and 1500 IU vial format
Switching patients (n = 16) | 500 IU | 1500 IU | CI/t(15) |
|---|---|---|---|
Thinking about when you were first trained to use C1-INH (Berinert®) 500/1500 IU, how would you rate the experience? (1 very difficult—5 very easy) | 3.2 (1.2) | 4.69 (0.6) | − 2.17 to − 0.83 − 4.74*** |
How would you rate the time it took you to master the administration of one treatment dose with C1-INH (Berinert®) 500/1500 IU vials? (1 very long—5 very fast) | 3.8 (1.1) | 4.7 (0.5) | − 1.71 to − 0.67 − 4.84*** |
How would you rate preparation and infusion time of one treatment dose with C1-INH (Berinert®) 500/1500 IU vials? (1 very long—5 very fast) | 3.1 (0.9) | 4.2 (0.8) | − 1.86 to − 0.38 − 3.2** |
How would you rate administration of one treatment dose with C1-INH (Berinert®) 500/1500 IU vials? (1 very hard—5 very easy) | 3.2 (1.3) | 4.5 (0.5) | − 1.88 to − 0.62 − 4.23*** |
How would you rate storage convenience of C1-INH (Berinert®) 500/1500 IU vials? (1 very poor—5 excellent) | 3.2 (1.2) | 4.9 (0.5) | − 2.38 to − 0.99 − 5.18*** |
How would you rate travel convenience of C1-INH (Berinert®) 500/1500 IU vials? (1 very poor—5 excellent) | 2.6 (1.0) | 4.7 (0.4) | − 2.75 to − 1.63 − 8.36*** |
Overall, how satisfied were you with C1-INH (Berinert®) 500/1500 IU? (1 very poor—5 excellent) | 3.8 (1.1) | 4.4 (1.1) | − 1.62 to − 0.37 n.s |
Naïve patients (n = 2) | 1500 IU | aCI/t | |
|---|---|---|---|
Thinking about when you were first trained to use C1-INH (Berinert®) 1500 IU, how would you rate the experience? (1 very difficult—5 very easy) | 3.5 (2.1) | − 17.09 to 19.47 n.s | |
How would you rate the time it took you to master the administration of one treatment dose with C1-INH (Berinert®) 1500 IU vials? (1 very long—5 very fast) | 3.5 (2.1) | − 17.43 to 19.55 n.s | |
How would you rate preparation and infusion time of one treatment dose with C1-INH (Berinert®) 1500 IU? (1 very long—5 very fast) | 4.0 (0.0) | − 1.09 to 1.47 n.s | |
How would you rate administration of one treatment dose with C1-INH (Berinert®) 1500 IU vials? (1 very hard—5 very easy) | 4.5 (0.7) | − 0.84 to 0.84 n.s | |
How would you rate storage convenience of C1-INH (Berinert®) 1500 IU vials? (1 very poor—5 excellent) | 4.5 (0.7) | − 0.44 to 1.19 n.s | |
How would you rate travel convenience of C1-INH (Berinert®) 1500 IU vials? (1 very poor—5 excellent) | 5.0 (0.0) | − 0.94 to 0.44 n.s | |
Overall, how satisfied are you with C1-INH (Berinert®) 1500 IU? (1 very poor—5 excellent) | 4.5 (0.7) | − 1.77 to 1.64 n.s |