Frequency of CD4+ and CD8+ T cells in Iranian chronic rhinosinusitis patients

Table 3 Comparison of Immunohistochemistry and real-time PCR results in controls and CRS patients

	Control	CRSsNP	CRSwNP	Control vs CRSsNP P value	Control vs CRSwNP P value	CRSwNP vs CRSsNP P value
Eosinophil	0.5 (0.5–1.5)	5.25 (4–7.37)	25 (7–37.5)	0.003	< 0.0001	0.013
Neutrophil	0.5 (0.5–1.5)	8.25 (6.25–10.5)	4 (2.5–6)	< 0.0001	0.001	0.014
Total inflammatory cells	12.5 (10–20)	42.25 (34–54.5)	91.5 (68.5–129)	0.004	< 0.0001	0.012
CD4 T cell	1 (1–1)	2 (2–2.75)	4 (3–6)	0.016	< 0.0001	0.006
CD8 T cell	1 (1–1)	6.5 (4.25–8.75)	20 (6–29)	< 0.0001	< 0.0001	NS
Macrophage	1 (0–1)	6.5 (5–8)	12 (9–15)	0.003	< 0.0001	0.013
Mononuclear cells	8 (6–13)	13.5 (8.25–19.5)	30 (15–35)	NS	< 0.0001	0.010
Goblet cells	16.5 (10.5–21.5)	14 (10.25–17.5)	7.70 (5.5–13.5)	NS	0.004	0.026
Mucosal glands	22.5 (15.5–35)	19 (15.25–22.75)	14 (7.5–27.5)	NS	NS	NS

NS not significant
Values are expressed as median (IQR). Kruskal–Wallis test was used for unpaired comparisons. Pv < 0.05 was considered statistically significant

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