Fig. 5

Frequency of TNFα producing myeloid dendritic cells (mDCs) (a) and amount of TNFα produced per cell (MFI) (b), with (activated state) or without activation (basal state) with Dermatophagoides pteronyssinus, in the control group, non-SIT group and SCIT group, immediately before treatment (T0) or 4 h after (T4). Mann–Whitney U test was used to compare control, non-SIT and SCIT-T0/T4 groups. Student’s t test was used to compare SCIT-T0 versus the SCIT-T4 group. The results were given by median with interquartile range. Statistical significant differences were considered when p < 0.05; *between the groups indicated in the figure