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Table 2 Post-BT changes in cardiopulmonary function assessed at THR during CPET

From: Improvement of exertional dyspnea and breathing pattern of inspiration to expiration after bronchial thermoplasty

 

Pre-BT

3 months after BT

1 year after BT

Dyspnea, Borg scale

7

4

4

HR response, %

105

109

103

Exercise time, min

9.6

14.5

15.5

\( {\dot{\text{V}}}_{{{\text{O}}_{ 2} }} \), mL min−1 kg−1

26.0

25.7

25.0

\( {\dot{\text{V}}}_{\text{E}} \), L min−1

79.4

75.4

75.3

ΔFO2, %

2.97

3.09

3.04

VTex, mL

2412

2495

2559

VT in − VTex, mL

6

23

− 64

fR, breaths min−1

32.9

30.2

29.4

Ti/Ttot

0.39

0.37

0.39

VD/VTex

0.28

0.28

0.27

\( {\dot{\text{V}}}_{\text{E}} /{\dot{\text{V}}}_{{{\text{O}}_{ 2} }} \)

41

41

41

\( {\dot{\text{V}}}_{\text{E}} /{\dot{\text{V}}}_{{{\text{CO}}_{ 2} }} \)

38

35

36

SpO2, %

91

96

94

AT, mL min−1

1147

1277

1230

  1. AT anaerobic threshold obtained by the V-slope method, BT bronchial thermoplasty, CPET cardiopulmonary function testing, ΔFO2 the inspired oxygen concentration (FiO2) minus the expired oxygen concentration (FeO2), ex expiratory, fR breathing frequency, HR heart rate, in inspiratory, SpO2 oxygen saturation, Ti/Ttot the ratio of inspiratory time to total breathing cycle time, THR target heart rate = 220 − age (years), \( \dot{V}_{{CO_{2} }} \) carbon dioxide output, VD/VTex physiologic dead space/tidal volume ratio, \( \dot{V}_{E} \) minute ventilation, \( \dot{V}_{{O_{2} }} \) oxygen uptake, VT tidal volume