From: Drug allergy
Patient-related factors |
 •Age: young/middle-aged adults > infants/elderly |
 •Gender: Women > men |
 •Genetic polymorphisms |
 •Viral infections: HIV, herpes viruses |
 •Previous reaction to the drug |
Drug-related factors |
 •High molecular weight compounds and hapten-forming drugs are more immunogenic |
 •Route: topical > IV/intramuscular > oral |
 •Dose: frequent/prolonged > single dose |