From: Hyper IgE recurrent infection syndrome in South Asia: is there a different outcome?
Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |
---|---|---|---|---|---|
Age at diagnosis and sex | 15 years, male | 5 years, female | 9 years, female | 7 years, female | 11 years, male |
Age at onset | Neonatal period | 2 months | Neonatal period | Neonatal period | 4 months |
Neonatal skin rash | Yes | No | Yes | Yes | No |
Dermatitis | Yes | Yes | Yes | Yes | Yes |
Candidiasis | Oral | Oral | No | No | No |
Respiratory infections | Recurrent LRTI, pyo-pneumothorax at 3 months Recurrent OM | Recurrent URTI, OM | Recurrent OM | Recurrent OM Recurrent pneumonia (×3), post varicella pneumonia | Pyo-pneumothorax |
Pneumatoceles | Yes | No | Yes | Multiple | No |
Abscesses | Skin | No | Skin | Skin, peri-pancreatic | Skin, dento-alveolar, lung |
Meningitis | No | Yes, recurrent (11 months, 2 years) | No | No | No |
Other infections | No | No | No | Pericardial effusion | No |
Retained teeth | Yes | No | Yes | Yes | |
Fractures | Bilateral radius and ulna | No | No | No | Right ulna |