Table 3 NIH Score based on [14]
From: Hyper IgE recurrent infection syndrome in South Asia: is there a different outcome?
Feature | Score | ||||
|---|---|---|---|---|---|
Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | |
Highest serum IgE level | 10 | 10 | 10 | 10 | 10 |
Skin abscess | 8 | 0 | 8 | 8 | 8 |
Pneumonia | 8 | 0 | 0 | 6 | 0 |
Parenchymal lung abnormalities | 8 | 0 | 8 | 8 | 6 |
Retained primary teeth | 1 | 0 | 2 | 2 | 0 |
Scoliosis | 0 | 0 | 0 | 0 | 0 |
Fractures with minor trauma | 8 | 0 | 0 | 0 | 4 |
Highest eosinophil count | 6 | 6 | 0 | 6 | 0 |
Characteristic face | 5 | 2 | 0 | 5 | 0 |
Midline anomaly | 0 | 0 | 0 | 0 | 0 |
Newborn rash | 4 | 0 | 4 | 4 | 0 |
Eczema | 4 | 2 | 1 | 0 | 0 |
URTI/year | 4 | 4 | 0 | 0 | 0 |
Candidiasis | 1 | 1 | 0 | 0 | 0 |
Other serious infections | 0 | 4 | 0 | 4 | 0 |
Fatal infections | 0 | 0 | 0 | 4 | 0 |
Hyperextensibility | 0 | 0 | 4 | 0 | 0 |
Lymphoma | 0 | 0 | 0 | 0 | 0 |
Increased nasal width | 1 | 0 | 0 | 0 | 0 |
High palate | 2 | 0 | 0 | 2 | 0 |
Young age correction | |||||
Total | 70 | 29 | 37 | 59 | 28 |
STAT3 mutation | Yes | Yes | Yes | Yes | Yes |