Hematopoietic cell transplantation for asymptomatic X-linked lymphoproliferative syndrome type 1

Table 1 HCT for asymptomatic patients with XLP1

Age	Donor Source	HLA matching	Conditioning regimen	GVHD prophylaxis	aGVHD	cGVHD	Outcome	References
1 years	Unrelated BM	6/6	Bu/TAI 3 Gy/Flu/CY/ATG	Tacrolimus/sMTX	None	None	Alive (3 years)	[5]
8 months	Unrelated PBSC	5/6	Flu/Mel/ATG/TAI 6 Gy	Tacrolimus/sMTX/PSL	GradeII	None	Alive (9 years)	[5]
20 months	Unrelated BM	8/8	Flu/Mel/TBI 3 Gy	Tacrolimus/sMTX	GradeI	None	Alive (2 years)	Our patient

aGVHD acute graft versus host disease, ATG anti thymocyte globulin, BM bone marrow, Bu busulfan, cGVHD chronic graft versus host disease, CY cyclophosphamide, Flu fludarabine, Mel melphalan, PBSC peripheral blood stem cells, PSL prednisolone, sMTX short term methotrexate, TAI total abdominal irradiation, TBI total body irradiation

ISSN: 1710-1492