Table 1 Comparison of patients between HR and LR groups
From: Airway reversibility in asthma and phenotypes of Th2-biomarkers, lung function and disease control
Variable | HR group (n = 60) | LR group (n = 205) | P value |
|---|---|---|---|
Gender (male) | 30 (50.0%) | 82 (40.0%) | 0.17 |
Age (years) | 45 ± 10 | 47 ± 13 | 0.23 |
BMI (kg/m2) | 22.80 ± 3.34 | 23.50 ± 4.07 | 0.23 |
Smoker (yes) | 21 (35.0%) | 90 (43.9%) | 0.22 |
Self-reported history of allergy (yes) | 7 (11.7%) | 42 (20.5%) | 0.12 |
Eosinophil count in blood (10^9/L) | 0.49 ± 0.28 | 0.36 ± 0.19 | < 0.01 |
IgE in blood (ng/ml) | 1306.0 ± 841.5 | 413.4 ± 261.6 | < 0.01 |
High-dose ICS+LABA | 2 (3.3%) | 3 (1.5%) | 0.69 |
Lung function test | |||
Pre inhaling short-acting bronchodilator | |||
FVC (L) | 3.01 ± 2.62 | 2.69 ± 0.84 | 0.14 |
FEV1 (L) | 1.52 ± 0.62 | 1.69 ± 0.65 | 0.08 |
FEV1%pred (%) | 51.91 ± 19.34 | 60.42 ± 19.22 | < 0.01 |
FEV1/FVC (%) | 55.43 ± 11.97 | 61.94 ± 12.59 | < 0.01 |
PEF (L/s) | 3.60 ± 1.49 | 3.88 ± 1.61 | 0.23 |
PEF%pred | 43.70 ± 16.80 | 50.59 ± 18.86 | 0.01 |
FEF50 (L/s) | 0.97 ± 0.50 | 1.23 ± 0.75 | < 0.01 |
FEF50%pred (%) | 23.05 ± 12.18 | 30.75 ± 17.26 | < 0.01 |
FEF75 (L/s) | 0.39 ± 0.40 | 0.69 ± 1.07 | < 0.01 |
FEF75%pred (%) | 19.05 ± 9.16 | 25.96 ± 16.08 | < 0.01 |
FEF25–75 | 0.76 ± 0.37 | 1.00 ± 0.67 | < 0.01 |
FEF25–75%pred (%) | 21.15 ± 10.09 | 29.06 ± 16.50 | < 0.01 |
Post inhaling short-acting bronchodilator | |||
FVC (L) | 2.73 ± 0.99 | 2.79 ± 0.85 | 0.67 |
FEV1 (L) | 2.11 ± 0.98 | 1.84 ± 0.68 | 0.02 |
FEV1%pred (%) | 72.45 ± 32.46 | 67.56 ± 26.88 | 0.23 |
FEV1/FVC (%) | 81.69 ± 38.48 | 65.73 ± 16.38 | < 0.01 |
PEF (L/s) | 4.12 ± 1.54 | 4.12 ± 1.69 | 0.98 |
PEF%pred | 50.09 ± 17.85 | 53.12 ± 18.96 | 0.27 |
FEF50 (L/s) | 1.38 ± 0.75 | 1.46 ± 0.81 | 0.51 |
FEF50%pred (%) | 33.12 ± 16.20 | 36.69 ± 18.64 | 0.15 |
FEF75 (L/s) | 0.58 ± 0.59 | 0.76 ± 0.97 | 0.08 |
FEF75%pred (%) | 27.84 ± 14.14 | 31.28 ± 18.86 | 0.13 |
FEF25-75 | 1.15 ± 0.65 | 1.50 ± 4.40 | 0.28 |
FEF25–75%pred (%) | 30.99 ± 16.96 | 44.60 ± 136.36 | 0.17 |
FEV1 changea | 30.13 ± 9.69 | 8.83 ± 9.11 | < 0.01 |
ACT score | 22 ± 4 | 20 ± 4 | 0.01 |