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Table 1 Products assessed by skin prick test and basophil activation test

From: Immediate hypersensitivity to polyethylene glycols in unrelated products: when standardization in the nomenclature of the components of drugs, cosmetics, and food becomes necessary

Drugs (active ingredients)

Contains PEG

Prick test

BAT

GripaNait® cough syrup

(paracetamol, dextromethorphan, doxylamine)

+

(macrogol 6000)

+

NP

Betadine® solution

(iodopovidone)

+

(laureth-9)

+

NP

Betadine® gel

(iodopovidone)

+

(PEG 400, 4000 and 6000)

+

NP

Romilar® tablets

(dextromethorphan)

Dormidina® 25 mg tablets

(doxylamine)

+

(PEG 8000)

+

+

Dormidina® 12.5 mg

tablets (doxylamine)

+

(PEG 400 and 6000)

Weak +

NP

Cariban® tablets

(doxylamine, pyridoxine)

NP

Polaramine® solution

(dexchlorpheniramine)

Soñodor® tablets

(diphenhydramine)

Atarax® solution

(hydroxyzine)

NP

FLUIDASA® solution

(mepyramine)

Cetirizine solution

(cetirizine)

NP

CETIRIZINE tablets

(cetirizine)

+

(macrogol 4000)

+

+

Ebastel® tablets

(ebastine)

+

(macrogol 6000)

+

+

Ebastel® solution

(ebastine)

+

(oxyethylene polymer)

+

+

Bilaxten® tablets

(bilastine)

Loratadine tablets

(loratadine)

NP

Movicol® powder

(macrogol 3350, sodium chloride, sodium bicarbonate, potassium chloride)

+

(macrogol 3350)

+

+

PEG 1500

(1% and 10%)

+

(PEG 1500)

NP

PEG 4000

(1%)

+

(PEG 4000)

+

+

ORAL-B® toothpaste

+

(PEG-6)

Ziverel® powder

(hyaluronic acid, chondroitin sulfate)

+

(poloxamer 407)

+

+

Polysorbate 80

(1% and 20%)

+

(polysorbate 80)

− in 1%

+ in 20%

− at 0.002 mg/ml

+ at 0.02 mg/ml

Citrafleet® powder

(sodium picosulfate, magnesium oxide, citric acid)

Paracetamol tablets

  1. BAT basophil activation test, NP not performed, PEG polyethylene glycol