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Table 1 Products assessed by skin prick test and basophil activation test

From: Immediate hypersensitivity to polyethylene glycols in unrelated products: when standardization in the nomenclature of the components of drugs, cosmetics, and food becomes necessary

Drugs (active ingredients) Contains PEG Prick test BAT
GripaNait® cough syrup
(paracetamol, dextromethorphan, doxylamine)
+
(macrogol 6000)
+ NP
Betadine® solution
(iodopovidone)
+
(laureth-9)
+ NP
Betadine® gel
(iodopovidone)
+
(PEG 400, 4000 and 6000)
+ NP
Romilar® tablets
(dextromethorphan)
Dormidina® 25 mg tablets
(doxylamine)
+
(PEG 8000)
+ +
Dormidina® 12.5 mg
tablets (doxylamine)
+
(PEG 400 and 6000)
Weak + NP
Cariban® tablets
(doxylamine, pyridoxine)
NP
Polaramine® solution
(dexchlorpheniramine)
Soñodor® tablets
(diphenhydramine)
Atarax® solution
(hydroxyzine)
NP
FLUIDASA® solution
(mepyramine)
Cetirizine solution
(cetirizine)
NP
CETIRIZINE tablets
(cetirizine)
+
(macrogol 4000)
+ +
Ebastel® tablets
(ebastine)
+
(macrogol 6000)
+ +
Ebastel® solution
(ebastine)
+
(oxyethylene polymer)
+ +
Bilaxten® tablets
(bilastine)
Loratadine tablets
(loratadine)
NP
Movicol® powder
(macrogol 3350, sodium chloride, sodium bicarbonate, potassium chloride)
+
(macrogol 3350)
+ +
PEG 1500
(1% and 10%)
+
(PEG 1500)
NP
PEG 4000
(1%)
+
(PEG 4000)
+ +
ORAL-B® toothpaste +
(PEG-6)
Ziverel® powder
(hyaluronic acid, chondroitin sulfate)
+
(poloxamer 407)
+ +
Polysorbate 80
(1% and 20%)
+
(polysorbate 80)
− in 1%
+ in 20%
− at 0.002 mg/ml
+ at 0.02 mg/ml
Citrafleet® powder
(sodium picosulfate, magnesium oxide, citric acid)
Paracetamol tablets
  1. BAT basophil activation test, NP not performed, PEG polyethylene glycol