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Table 3 Clinical data for the outliner patient belonging to the low serum total IgE (sIgEtot) subgroup (see Fig. 1b)

From: Variability in total serum IgE over 1 year in severe asthmatics

Visit Baseline 1 2 3 4 5 6
sIgEtot (IU/mL) 61.3 41 43 818 1159 357 266
FEV1 predicted (%) 49   61 64 52 59 65
Total ACQ score 13 19 14 25 19 15 16
FENO (ppm) 7.1   4.8 18.6    28.1
Asthma exacerbation x x x x x   
Asthma exacerbation requiring OCS (if yes dosis mg)     32 16   
Parasitic infection     x    
 Budesonide/formoterol (µg/days) 1200/54 1200/54 800/36 1200/54 1200/54 1200/54 1200/54
 OCS dosis (mg/days) 16 16 8 16 16 16 16
 Beclamethasone/formoterol   200/18 200/18    200/18 200/18
 Salbutamol x    x x   
 Fenoterol/ipratropium    x     
 Theophylline x   x x   x x
 Azythromycine x x x     
  1. FEV1, forced expiratory volume in 1 s; FENO, fractional exhaled nitric oxide; OCS, oral corticosteroids