Table 2 Intraclass correlation coefficients (95% CI) by physiological and blood biomarker
From: Stability of peripheral blood immune markers in patients with asthma
All subjects (n = 19) | Females (n = 12) | |
|---|---|---|
Physiological biomarkers | ||
FEV1 (% predicted) | 0.90 (0.78–0.95) | 0.92 (0.76–0.96) |
FEV1/FVC | 0.79 (0.57–0.89) | 0.80 (0.49–0.91) |
ACQ5 | 0.68 (0.44–0.82) | 0.72 (0.40–0.86) |
ACQ7 | 0.75 (0.52–0.87) | 0.78 (0.46–0.91) |
Blood biomarkers | ||
Eosinophils | ||
% Eosinophils in PB (Kimura staining) | 0.44 (0.10–0.67) | 0.50 (0.10–0.76) |
% Eosinophils in PB (flow cytometry) | 0.52 (0.24–0.71) | 0.43 (0.06–0.68) |
Innate lymphoid cells (ILC2) | ||
% ILC2 in PB | 0.45 (0.14–0.67) | 0.58 (0.08–0.75) |
T cell subsets | ||
% CD4+CRTh2+T cells in PB | 0.17 (0.00–0.40) | 0.24 (0.00–0.52) |
% of CD4+ T cells expressing CRTh2 | 0.31 (0.04–0.53) | 0.35 (0.00–0.62) |
Monocyte subsets | ||
% CD14++CD16+ (intermediate) monocytes in PB | 0.06 (0.00–0.28) | 0.00 (0.00–1.00) |
% CD14++CD16− (classical) monocytes in PB | 0.18 (0.00–0.41) | 0.06 (0.00–0.38) |
% CD14++CD16+PAR-2+ cells in PB | 0.24 (0.00–0.44) | 0.21 (0.00–0.50) |
% CD14++CD16+ cells expressing PAR-2 | 0.09 (0.00–0.31) | 0.22 (0.00–0.52) |
Dendritic cell (DC) subsets | ||
% myeloid DC (mDC) in PB | 0.19 (0.00–0.43) | 0.18 (0.00–0.47) |
% plasmacytoid DC (pDC) in PB | 0.30 (0.04–0.53) | 0.30 (0.00–0.60) |
% mDC expressing FcεR1α | 0.10 (0.00–0.32) | 0.12 (0.00–0.41) |
% pDC expressing FcεR1α | 0.32 (0.04–0.55) | 0.20 (0.00–0.51) |