Table 2 Crude and adjusted associations between M-values and asthma in the IOW F1 (18 years of age, n = 370) sample via logistic regression
From: Epigenome-wide association study of asthma and wheeze characterizes loci within HK1
CpG annotations | DNAm distribution | Crude model | Adjusted modela | ||||
|---|---|---|---|---|---|---|---|
CpG ID | Gene | Median | (5th, 95th pct.) | OR | CI | OR | CI |
cg00100703 | UNC45B | 0.93 | (0.89, 0.95) | 0.12 | (0.05, 0.28) | 0.18 | (0.06, 0.50) |
cg01069468 | SYNGAP1 | 0.88 | (0.84, 0.91) | 0.12 | (0.04, 0.31) | 0.39 | (0.08, 1.72) |
cg04359558 | LITAF | 0.93 | (0.87, 0.96) | 0.23 | (0.12, 0.42) | 0.34 | (0.17, 0.68) |
cg06866208 | – | 0.81 | (0.73, 0.84) | 0.14 | (0.05, 0.34) | 0.40 | (0.09, 1.72) |
cg07948085 | – | 0.89 | (0.84, 0.93) | 0.16 | (0.07, 0.34) | 0.26 | (0.09, 0.74) |
cg09241885 | C20orf118 | 0.89 | (0.80, 0.93) | 0.29 | (0.16, 0.49) | 0.41 | (0.17, 0.99) |
cg11310939 | MARCH3 | 0.91 | (0.86, 0.92) | 0.19 | (0.09, 0.40) | 0.45 | (0.15, 1.44) |
cg13753183 | APTX | 0.90 | (0.86, 0.93) | 0.11 | (0.04, 0.30) | 0.30 | (0.06, 1.38) |
cg16658191 | HK1 | 0.93 | (0.89, 0.95) | 0.12 | (0.05, 0.27) | 0.17 | (0.04, 0.57) |
cg25578728 | CHD7 | 0.90 | (0.85, 0.94) | 0.24 | (0.11, 0.46) | 0.27 | (0.11, 0.60) |