Table 5 Associations between cord blood DNAm at cg16658191 and expression of HK1 with infant wheeze without cold and any wheeze within the IOW F2 sample
From: Epigenome-wide association study of asthma and wheeze characterizes loci within HK1
Exposure | Outcomes | |||||
|---|---|---|---|---|---|---|
Wheeze without cough/cold | Any wheeze | |||||
OR | p-value | 95% CI | OR | p-value | 95% CI | |
cg16658191 (n = 111) | ||||||
 Crude model | 0.23 | 0.0097 | (0.07–0.68) | 0.58 | 0.23 | (0.23–1.41) |
 Adjusted model 1a | 0.21 | 0.0062 | (0.06–0.61) | 0.57 | 0.23 | (0.22–1.40) |
 Adjusted model 2b | 0.37 | 0.30 | (0.05–2.35) | 2.42 | 0.27 | (0.52–12.18) |
HK1 (A_23_P217958) (n = 82) | ||||||
 Crude model | 3.14 | 0.0183 | (1.26–8.62) | 3.44 | 0.0045 | (1.54–8.59) |
 Adjusted model 1a | 3.62 | 0.015 | (1.34–10.95) | 3.22 | 0.0075 | (1.42–8.08) |
 Adjusted model 2b | 7.51 | 0.0085 | (1.89–40.50) | 4.89 | 0.0087 | (1.63–18.15) |