Subject demographic | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 |
---|---|---|---|---|---|
Age (years) | 58 | 29 | 45 | 28 | 57 |
Sex | Female | Female | Female | Female | Female |
Asthma (history) | 10 years | 2 years | 5 months | 1 year | 4 months |
Lung function FVC (L/%) | 1.97 (87.7%) | 1.83 (53.6%) | 3.53 (137%) | 2.55 (70%) | 2.55 (70%) |
FEV1 (L/%) | 1.17 (62.6%) | 1.19 (40.1%) | 2.59 (121%) | 1.68 (54%) | 1.37 (68%) |
FEV1/FVC (%) | 59.52% | 65.04% | 73% | 65% | 53.54% |
PEF (L/%) | 2.80 (51.9%) | 3.28 (48.5%) | 6.68 (133%) | 4.66 (71%) | 2.14 |
Reversibility test | Positive | Positive | Negative | Negative | Positive |
FeNO (ppb) | 42 | 40 | 35 | 47 | 40 |
HRCT findings | Multiple infiltrates in lower left lung and ground-glass opacities in the subpleural regions of both upper lung fields | Multiple ground-glass opacities in the regions of both lung fields | Multiple small nodules in the upper lung | Multiple infiltrates in upper left lung, lower right lung and ground-glass opacities in the subpleural regions of both upper lung fields | Multiple infiltrates in upper left lung, lower right lung and ground-glass opacities in the subpleural regions of both upper lung fields |
Blood Eos (*10 ~ 9/L, %) | 1.17 (23.9%) | 1.86 (18.7%) | 0.64 (17.6%) | 1.57 (29.3%) | 1.31 (18.9%) |
Serum IgE (ng/ml) | 3715 | 7951 | 5697 | 3672 | 6120 |
Bronchial lavage eosinophils (%) | 14% | 16% | 27% | 28% | Not performed |
Treatment | |||||
Methylprednisolone 40 mg ivgtt 5 days + Budesonide and Formotero (160 µg, inhalation, Bid) | Done | Done | Done | Done | Done |
Blood Eos (*10 ~ 9/l, %) | 0.17 (4.0%) | 0.65 (12.2%) | 0.12 (1.5%) | 0.43 (0.2%) | 0.10 (0.1%) |
Lung function FVC (L/%) | 2.09 (93.04%) | 3.08 (92.4%) | Not performed | Not performed | 2.87 |
FEV1 (L/%) | 1.32 (67.7%) | 1.87 (64.3%) | 1.90 (83.1%) | ||
FEV1/FVC (%) | 63.00% | 60.57% | 68.76% | ||
PEF (L/%) | 3.45 (71.9%) | 4.6 (68.8%) | 6.09 | ||
Reversibility test | Positive | Positive | Positive | ||
FeNO (ppb) | 14 | 14 | 18 | ||
HRCT findings | Apparent absorption | Apparent absorption | Apparent absorption | Apparent absorption | Apparent absorption |