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Fig. 3 | Allergy, Asthma & Clinical Immunology

Fig. 3

From: Endogenous stimulation is responsible for the high frequency of IL-17A-producing neutrophils in patients with rheumatoid arthritis

Fig. 3

The frequency of IL-17A + neutrophils is elevated in patients with RA. a Representative flow cytometry plots for 3 patients and 3 healthy controls. b Frequency of IL-17A + neutrophils in patients (n = 106) and healthy controls (56). c Absolute numbers of IL-17A-positive neutrophils calculated using neutrophil absolute numbers from the clinical count, using the equation: \( \frac{{\# {\text{ total leukocytes }} \times \, \% {\text{ total neutrophils}}}}{100} \times \frac{{\% {\text{ IL}} - 1 7 {\text{A}} + {\text{ neutrophils X 1}}000}}{100} \). The Mann–Whitney U-test was utilized and resulted in a p value < 0.0001. d Correlation plot between IL-17A + neutrophils and DAS28-CRP. e Correlation graph between IL-17A-producing neutrophils and time after onset of the disease. A Spearman correlation test was performed for these samples. Error bars indicate SD

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