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Table 1 Differential frequency of Lymphocytes and serum levels of immunoglobulins in the patient

From: Graft versus host disease and microchimerism in a JAK3 deficient patient

Parameters

Patient

Normal rangea

WCB (cell*103/µL)

10.3b

5–17

Eosinophils  % (count, cell/mL)

8.2 (851)b

0–1

Platelets, count, cells*109/L

325b

150–400

Hemoglobin, g/dL

10.4b

11.5–14.0

Lymphocyte  % (count, cell/mL)

78.7 (8169)b

50–70

CD3% (count, cell/mL)

93.5 (7643)b

56–75

CD4% (count, cell/mL)

86.4 (7063)b

28–47

CD4+ CD45RA+ CD45RO− (naïve) % of helper T cells

59

11–53

CD4+ CD45RA-CD45RO+ (memory) % of helper T cells

28

31–74

CD4+ HLA-DR+ CD38− (activated) % of helper T cells

3

2–11

CD8% (count, cell/mL)

4.6 (382)b

16–30

CD8+ CD45RA+ CD45RO− (naïve) % of cytotoxic T cells

75

27–69

CD8+ CD45RA-CD45RO+ (memory) % of cytotoxic T cells

15

12–50

CD8+ HLA-DR+ CD38− (activated) % of % of cytotoxic T cells

2

2–22

CD16% (count, cell/mL)

4.2 (343.1)b

4–17

CD19% (count, cell/mL)

4.05 (331)b

14–33

Lymphocyte proliferation responses to PHA

1.5

> 0.3

Quantitative CD4+ PHA response (c/µL)

120b

170–3499

Quantitative CD8+ PHA response (c/µL)

25b

76–3640

IgG (mg/dL)

332b

295–1156

IgA (mg/dL)

5b

27–246

IgM (mg/dL)

87b

37–184

Anti-tetanus (IU/mL)

0.05b

> 0.1

Anti-diphtheria (IU/mL)

0.01b

> 0.1

TRECs

10c

23–67

  1. TRECs T-cell receptor excision circles, PHA phytohemagglutinin
  2. aThe normal range of these quantities is derived from the http://www.palms.com.au
  3. b Measured at age 10 months
  4. cMeasured at age 3 years