Skip to main content

Table 5 Comparison between the expression of extracellular matrix components and endothelial activation markers in pulmonary and bronchial arteries in asthma patients and controls

From: Structural alterations and markers of endothelial activation in pulmonary and bronchial arteries in fatal asthma

Marker

Bronchial artery

Pulmonary artery

Asthma

Control

p

Asthma

Control

p

Collagen I

0.59 (0.21–2.58)a

0.33 (0.08–4.69)a

0.689

5.15 ± 0.96

9.10 ± 3.79

0.340

Collagen III

22.51 ± 4.03

17.77 ± 6.30

0.527

17.16 (8.52–30.31)a

10.88 (3.25–32.29)a

0.533

Tenascin

38.39 ± 5.53

49.73 ± 11.23

0.315

30.92 (17.24–60.90)a

41.99 (20.41–81.83)a

0.449

Fibronectin

23.26 ± 3.02

32.52 ± 11.23

0.289

47.43 ± 4.70

45.18 ± 8.19

0.803

Versican

8.96 ± 2.24

7.44 ± 2.37

0.692

26.12 ± 3.16

16.96 ± 4.23

0.113

AT-2

7.84 ± 1.56

16.14 ± 6.32

0.235

8.29 ± 1.09

11.89 ± 2.95

0.287

ET-1

31.53 ± 6.19

36.19 ± 7.94

0.670

21.40 ± 2.77

26.27 ± 6.75

0.519

ICAM-1

5.10 ± 1.06

4.41 ± 1.84

0.735

5.56 ± 0.67

4.94 ± 0.88

0.603

VCAM-1

13.19 ± 10.71

3.97 ± 7.28

0.026

9.80 ± 6.20

9.72 ± 8.49

0.980

  1. Data represent the mean density
  2. AT-2 angiotensin II type 2 receptor, ET-1: endothelin-1, ICAM-1 intercellular adhesion molecule 1
  3. aData are presented as the mean ± SD or median (IQR)