Fig. 1

PRISMA diagram. PRISMA diagram of the study shows the methodology of selecting studies for the review. Results of searches from indexed databases (PUBMED, LILACS and Cochrane) and clinical trial registries (ClinicalTrials.gov, International Standard Randomised Controlled Trials Number -ISRCTN, International Clinical Trial Registry Platform—ICTRP) are shown parallel. After screening 732 entries from indexed databases and 95 entries from clinical trial registries 16 studies were included in qualitative analysis. Further 22 case reports and six small case series summarised