Table 2 OTI guidelines with Granini® peach juice
From: Oral immunotherapy with peach juice in patients allergic to LTPs
Stage 1. Sublingual 2 min and then spit out | |
Visit 1 (dilution 1/1000) | 1–2–4 drops |
Visit 2 (dilution 1/100) | 1–2–4 drops |
Visit 3 (dilution 1/10) | 1–2–4 drops |
Visit 4 (1/1: undiluted juice) | 1 drop |
Visit 5 (1/1) | 2 drops |
Visit 6 (1/1) | 4 drops |
Visit 7 (1/1) | 5 drops |
Stage 2. Sublingual 2 min and swallow (drops) | |
Visit 8 (1/1) | 1 drop |
Visit 9 (1/1) | 2 drops |
Visit 10 (1/1) | 4 drops |
Visit 11 (1/1) | 5 drops (equivalent to 0.13 ml) |
Stage 3. Sublingual 2 min and swallow (ml) | |
Visit 12 | 0.25 ml |
Visit 13 | 0.50 ml |
Visit 14 | 1 ml |
Visit 15 | 2 ml |
Visit 16 | 3 ml |
Visit 17 | 5 ml |
Stage 4. Oral tolerance test with whole juice | |
Visit 18 | 10–25–65–100 ml (accumulated dose 200 ml) |
Continue intake of 200 ml/day (1 carton), at least 4 days/week | |