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Table 1 Summary of X-linked and autosomal recessive forms of chronic granulomatous disease genes according to ethnic origin

From: A novel mutation in NCF2 resulting in very-early-onset colitis and juvenile idiopathic arthritis in a patient with chronic granulomatous disease

Publication [reference]Number and populationX-linkedaAutosomal recessivebType of autosomal recessive gene
Köker et al. [7]89 Turkish34 (38.2%)50 (56.2)CYBA (22.5%)
NCF1 (19.1%)
NCF2 (14.6%)
Van den Berg et al. [9]357 European265 (74.2%)92 (25.7%)NCF1 (16%)
CYBA (5.1%)
NCF2 (2.5%)
Unknown (8.6%)
12 Turkeyc4 (33%)8 (67%)
38 Arab/North Africanc11 (29%)27 (71%)
6 East and South Asia1 (17%)5 (83%)
16 Israeli/Jew9 (56%)7 (44%)
Wolach et al. [8]84 Israeli (Jew, Arabc, visitor)32 (38%)52 (62%)c
(64% consanguinity)
NCF1 (31%)
NCF2 (19%)
CYBA (12%)
Fattahi et al. [10]93 Iranianc12 (12.9%)81 (87.1%)NCF1 (55.5%)
Kulkarni et al. [11]90 Indianc
(32% consanguinity)
27 (30%)63 (70%)NCF1 (56%)
CYBA (7%)
NCF1 (7%)
  1. aCYBB, bNCF1, CYBA, NCF2, NCF4
  2. cReported high rate of consanguinity