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Table 1 Summary of X-linked and autosomal recessive forms of chronic granulomatous disease genes according to ethnic origin

From: A novel mutation in NCF2 resulting in very-early-onset colitis and juvenile idiopathic arthritis in a patient with chronic granulomatous disease

Publication [reference]

Number and population

X-linkeda

Autosomal recessiveb

Type of autosomal recessive gene

Köker et al. [7]

89 Turkish

34 (38.2%)

50 (56.2)

CYBA (22.5%)

NCF1 (19.1%)

NCF2 (14.6%)

Van den Berg et al. [9]

357 European

265 (74.2%)

92 (25.7%)

NCF1 (16%)

CYBA (5.1%)

NCF2 (2.5%)

Unknown (8.6%)

12 Turkeyc

4 (33%)

8 (67%)

38 Arab/North Africanc

11 (29%)

27 (71%)

6 East and South Asia

1 (17%)

5 (83%)

16 Israeli/Jew

9 (56%)

7 (44%)

Wolach et al. [8]

84 Israeli (Jew, Arabc, visitor)

32 (38%)

52 (62%)c

(64% consanguinity)

NCF1 (31%)

NCF2 (19%)

CYBA (12%)

Fattahi et al. [10]

93 Iranianc

12 (12.9%)

81 (87.1%)

NCF1 (55.5%)

Kulkarni et al. [11]

90 Indianc

(32% consanguinity)

27 (30%)

63 (70%)

NCF1 (56%)

CYBA (7%)

NCF1 (7%)

  1. aCYBB, bNCF1, CYBA, NCF2, NCF4
  2. cReported high rate of consanguinity