Table 1 Demographic and clinical characteristics of study participants
Characteristic | Control subjects | Patients with CRSsNP | Patients with CRSwNP | P |
|---|---|---|---|---|
No. | 21 | 28 | 48 | Â |
Gender (female/male) | 12/9 | 21/7 | 35/13 | 0.34 |
Age (years), median (range) | 44 (18–65) | 46.5 (19–68) | 56 (18–67) | 0.02 |
Allergy, no (%) | 1 (4.8) | 7 (25) | 11 (22.9) | 0.15 |
Asthma, no (%) | 0 (0) | 0 (0) | 5 (10.4) | 0.07 |
Smoking, no (%) | 5 (23.8) | 7 (25) | 18 (37.5) | 0.38 |
Drinking, no (%) | 6 (28.6) | 7 (25) | 17 (35.4) | 0.61 |
Serum total IgE (kU/I), median (range) | 43 (2–410) | 83.95 (6.04–577) | 48 (2.59–1017) | 0.38 |
Polyp score (Davos), median (range) | 0 | 0 | 3 (1-6) | < 0.001 |
Prior nasal surgeries, no (%) | 0 (0) | 0 (0) | 12 (25.0) | < 0.001 |
Olfactory score, median (range) | 1 | 1 (1–5) | 4 (1–5) | 0.003 |
Total nasal resistance (Pa/cm3/s), 75 Pa, median (range) | 0.116 (0–0.301) | 0.145 (0.095–0.357) | 0.073 (0–8.163) | 0.041 |
Unilateral nasal resistance (Pa/cm3/s), 75 Pa, mean (range) | 0.276 (0.150–0.685) | 0.373 (0.200–0.737) | 0.463 (0.141–16.811) | 0.001 |
Total nasal resistance (Pa/cm3/s), 150 Pa, median (range) | 0.139 (0–0.354) | 0.190 (0–0.441) | 0.247 (0–11.768) | 0.045 |
Unilateral nasal resistance (Pa/cm3/s), 150 Pa, mean (range) | 0.303 (0.199–0.797) | 0.507 (0.244–2.371) | 0.614 (0.121–23.703) | 0.001 |