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Table 2 Multivariate analysis of factors influencing methylation ratios at CpG3 and CpG22:23:24 sites within TSLP promoter

From: Association between methylation in nasal epithelial TSLP gene and chronic rhinosinusitis with nasal polyps

Factors

Standardized beta

95% CI

P

CpG3

 Disease status

0.26

0.001–0.006

0.019

 Gender

− 0.11

− 0.008–0.003

0.38

 Age

0.25

2.6E−5–3.8E−4

0.025

 Smoking

− 0.13

− 0.009–0.003

0.32

 Drinking

− 0.01

− 0.006–0.006

0.92

 Comorbid asthma

0.08

− 0.007–0.014

0.47

 Allergic disease

− 0.03

− 0.006–0.005

0.77

CpG22:23:24

 Disease status

0.31

0.002–0.009

0.006

 Gender

0.04

− 0.006–0.009

0.73

 Age

0.08

− 1.5E−4–3.3E−4

0.48

 Smoking

− 0.16

− 0.01–0.003

0.23

 Drinking

0.15

− 0.004–0.013

0.27

 Comorbid asthma

− 0.17

− 0.02–0.002

0.10

 Allergic disease

− 0.04

− 0.009–0.006

0.72

  1. Italic values indicate significance of P value (P < 0.05)