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Fig. 3 | Allergy, Asthma & Clinical Immunology

Fig. 3

From: Mechanism(s) of prolonged attenuation of allergic responses after modulation of idiotypic regulatory network

Fig. 3

As for Fig. 2, but now showing attenuation of OVA-specific IgE and OVA-induced IL-4 (a, c) but not IgG and OVA-induced IL-2 (b, d) in groups of naïve 8 BALB/c mice immunized with OVA in alum (see “Materials and methods”) and in addition receiving pooled human anti-Tet immune Ig serum alone (10 μg/mouse), human IMIG alone (75 μg/mouse), or a combination of the two antibodies at weekly intervals (×5 injections). *p < 0.05 compared with mice receiving normal mouse serum (OVA); **p < 0.05 compared with OVA + EWS group

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