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Table 1 Surviving CD4+/CD8+ cells in splenocytes of mice shown in Figs. 6 and 7

From: Mechanism(s) of prolonged attenuation of allergic responses after modulation of idiotypic regulatory network

Group of mice

a %CD4+ b

% CD8+ b

Control Ig

23 ± 4.1

7.1 ± 2.2

Control C1

6.3 ± 1.5*

2.5 ± 0.6*

Control C2

26 ± 3.8

7.0 ± 2.5

Anti-CD4 treated

6.0 ± 2.1*

10 ± 2.9

Anti-CD8 treated

27 ± 5.5

1.9 ± 0.5*

Anti-CD4+ anti-CD8 treated

6.7 ± 2.8*

2.0 ± 1.2*

  1. aMice were immunized with OVA; received additional treatment with combined anti-idiotype and immune Ig; and also, anti-CD4 and/or anti-CD8 as indicated in Figs. 6 and 7
  2. b% positive CD4+ and CD8+ cells in splenocytes of mice treated as in Fig. 6 and sacrificed 10 days after the last OVA immunization. Data show means (± SD) for groups of 7 mice
  3. * p < 0.05 compared with first row, control Ig group (no anti-idiotype Ig/Immune Ig and no anti-CD4/-CD8)
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Allergy, Asthma & Clinical Immunology

ISSN: 1710-1492

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