A preseason booster prolongs the increase of allergen specific IgG4 levels, after basic allergen intralymphatic immunotherapy, against grass pollen seasonal allergy

Table 1 Side effects

	A	B	C	D
1	ILIT-injection × 3 basic treatment 2015 + booster-inj 2016	Basic ILIT treatment 1-3 and 39 injections	Active booster 13 injections	Placebo booster 6 injections
2	Nose within 1 h	0	0	0
3	Lungs within 1 h	0	0	0
4	skin within 1 h	0	0	0
5	Abdomen within 1 h	0	0	0
6	Local redness within 1 h	1	1	0
7	Local swelling within 1 h	4	4	0
8	Local itch within 1 h	3	0	0
9	Local bruising within 1 h	0	0	0
10	Nose within 24 h	4	2	0
11	Lungs within 24 h	0	0	0
12	Skin within 24 h	3	1	0
13	Abdomen within 24 h	0	0	0
14	Tiredness within 24 h	16	3	1
15	Local redness within 24 h	7	5	0
16	Local swelling within 24 h	6	2	0
17	Local within 24 h	9	4	0
18	Local bruising within 24 h	0	0	0
19

The numbers indicate how many injections that caused the various side effects, respectively. In this project there were no local bruising

ISSN: 1710-1492